Commercial Real Estate

Downtown Waynesville - Historic Route 66 - West Waynesville


Why Waynesville?  

Hands down, Waynesville is the best place to launch your new business venture, in Pulaski County.  We pride ourselves in a strong economy, diverse population, great educational institutions and unsurpassed quality of life which makes Waynesville the ideal place to do business.  Focusing less on quantity and more on the quality of the businesses that choose to make Waynesville home, insures that the climate for business is inviting and sustainable.  

The first step in starting any business is finding the right property to invest your dreams in.  The City is extrememly proud of its business community and through that partnership, we are able to provide current information on available commercial properties within the City.   Be sure to check out these amazing propertes listed below and check back often as new properties are added regularly!  

If you are a commercial property owner in Waynesville and would like your property showcased either for rent or sale, reach out to us at 

Waynesville Downtown

Roubidoux Plaza - N. Benton Street

FOR RENT - With one of the best locations in Waynesville, Roubidoux Plaza offers modern amenities with a vintage feel.  With spaces ranging from 500 to 700 square feet, these available properties are perfect for boutiques, small cafès, speciality shops and more. The only limit is your imagination!

Take advantage of the heartbeat of the Downtown District and make the Roubidoux Plaza pulse with your innovation and business sense!

For more information contact JUL,LLC at 573.855.0421 or you can reach them on their Facebook page.  

Hurry! These spaces won't last long!!


213 North Street

FOR SALELocated on the corner of North Street and North Benton, this gem of a place sits right across from the Pulaski County Courthouse and City of Waynesville Post Office.

This building has been used as a medical office previously, but could easily be molded to fit any need.  Parking is ample with a city parking lot located behind the building.

For more information, contact Cross Creek Realty, LLC through their website or by calling 573.774.3500.


405 North Street

FOR SALESuch an incredible opportunity!  This historical beauty dates back to 1885.  

Currently an antique shop, this property would make a wonderful bed & breakfast or continue as a boutique!  With a wonderful corner lot and plenty of space, this property lends its self to many different uses.  Be sure and check this one out today!

Head over to to the realtor's website or give them a call at 573.336.3535


215 Historic Route 66 East

FOR SALE - Looking for Route 66 frontage right in the middle of a vibrant downtown?  Then look no further!  Commercially zoned and ready for your business plan.

Ideal for retail, office, boutiques, restaurant or hotel.  Take advantage of the downtown traffic and build your dream on Historic Route 66!

More information regarding this amazing property can be found here


Historic Route 66

207 Historic Route 66 West

FOR SALEIf your dream has been to own a piece of the Mother Road, look no further!  Sitting within walking distance of downtown and the Roubidoux, this older commercial building is rich in local history.

This opportunity won't last long!  You can find out more information on this unique property here!



1904 Historic Route 66 West

FOR SALEWith more than two acres and plenty of Route 66 Frontage, this amazing piece of property services not only Route 66 but Hwy T as well.

Surrounded by new subdivisions, the property was rezoned to Commercial in preparation to service the newly constructed housing areas located in West Waynesville.  More information on this property can be found here.




Hwy 17 & Cash James Loop

FOR SALE - With over an acre of prime real estate less than a 1/4 of a mile from one of Waynesville's busiest intersections, this amazing property won't last long.  

With utilities and other key infrastructure in place, this site is ready for your next business venture.  You can find out more information on this property here.


Hwy 17 & Ichord Avenue


FOR SALE Sitting at the corner of a busy intersection and right beside a popular retail chain, this property has loads of potential.  

Whether it's a franchise or specialty shop, this site is perfect for any business opportunity.

If you are interesting in this property, more information can be found here.



West Waynesville

308 Ichord Avenue

FOR SALE OR LEASE This property has an awesome location, right at the intersection of Ichord Avenue and GW Lane.  With the Waynesville High School right up the road, Interstate 44 at your feet and the main corridor to Fort Leonard Wood's west gate, the traffic never stops!  Zoned Commercial, this property won't last long!  Find out more information here

308 Ichord Avenue - Marketing Brochure






Ichord Avenue & CW Parker

FOR SALE With Ichord Avenue frontage and nestled between two popular retail chains, this property has tons of potential!  Located right off of Historic Route 66, this prime piece of real estate is ready for your next big business adventure.  Click here for more information.




102 Ashley May Lane


FOR SALE - High Visibility with this great commercial building where your possibilities are endless. This building offers over 15000 sg ft with 2 suites, both ready to make it your own space while renting out the other side for income! Both sides offer individual heating/cooling and separate 3 phase electric, both offering overhead doors and extra storage. You will be impressed with the steel frame contraction, brink front and oversized asphalt parking lot. Ideally located next to shopping, schools and banks.



Davis Center Properties - 320 Ichord Avenue

FOR LEASEThis property has been beautifully updated.  Currently three (3) spaces available but two could be combined for the right business.  Newly paved, well lit parking lot with restrooms.  Perfect for retail, restaurant, etc.  Come be a part of the action in West Waynesville!  Town Field Plaza information.


Contact Info

Doug Potts
Economic Development Coordinator

John Doyle
City Administrator
100 Tremont Center

Michele Brown
City Clerk